Herpes simplex

Fachleiter

Description

Typical are grouped small blisters on a reddened base.

The blisters may burst, ooze and later crust over. Often burning, tingling, or a feeling of tension precedes them.

Fachleiter

Location

  • Commonly on the lips (‘cold sores’)
  • Corners of the mouth
  • Nose / nostril
  • Cheek or chin
  • Rarely the eye area (caution!)

Fachleiter

Symptoms and Course

ColloquialMedical term
Tingling or burningProdromal stage
Small blistersVesicular lesions
Pain / burningDolor / burning
CrustingCrust formation
Recurrent episodesRecurrent infection
Typical course
1. Tingling/Burning
2. Blister formation
3. Rupture/Oozing
4. Crust formation
5. Healing usually within 7–14 days

Fachleiter

Cause / Triggers

Cause

  • Caused by the herpes simplex virus type 1 (HSV-1), less commonly HSV-2.
  • After the primary infection the virus remains in the body for life and can be reactivated.

Common triggers

  • Stress
  • Fever / infections
  • UV radiation / sun
  • Weakened immune system
  • Lack of sleep

Fachleiter

Treatment

Active ingredient (generic)Brand nameFormDoseUseImportant notes / side effects
AciclovirZovirax®Cream 5 %Apply thinly 5 times dailyUse early at tingling/burningLocal skin irritation or burning possible
PenciclovirFenistil Pencivir®Cream 1 %Every 2 hours during the dayParticularly effective in the early phaseSkin irritation possible
AciclovirAcic® / Zovirax®Tablets400 mg 3 times daily or 200 mg 5 times dailyFor more severe outbreaks or frequent recurrencesNausea, headaches; monitor kidney function
ValaciclovirValtrex®Tablets500–1000 mg 2 times dailyEasier dosing due to longer duration of actionHeadache, nausea possible
ParacetamolBen-u-ron® / Paracetamol-ratiopharm®Tablets500–1000 mg as neededFor pain or feverObserve maximum dose
IbuprofenNurofen® / Ibuflam®Tablets400 mg as neededFor pain and inflammationCaution with stomach problems or kidney disease

Fachleiter

Important considerations

  • Exclude eye involvement!
  • Do not pick at the blisters
  • Wash hands regularly
  • No kissing during active blisters
  • No shared towels / lip care products
  • Use lip sun protection

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